Have We Found the Fountain of Youth?


These of you following my DrDavisInfiniteHealth.com weblog, in addition to its predecessor, the Wheat Stomach Weblog, know that I’m a giant fan of the microbe, Lactobacillus reuteri, L. reuteri.

Recall that L. reuteri is ubiquitous in human populations unexposed to antibiotics and different microbiome-disruptive components distinctive to trendy life. If we had been to due to this fact analyze the intestinal microbiome of native New Guineans who spear or membership their subsequent meal, dig within the filth for roots and tubers, collect berries, birds, eggs, mushrooms, drink from rivers and puddles, haven’t any working water, and so forth. all of them have L. reuteri. If we had been to evaluate the intestinal microbiomes of wolves, squirrels, rabbits, or deer within the forest, who likewise eat meals foraged from the wild, all of them have L. reuteri. Sequence the intestinal microbiome of a contemporary American, nevertheless, and you might be unlikely to seek out L. reuteri—almost all of us have misplaced this microbe. The German microbiologist, Dr. Gerhard Reuter, who first recognized this microbe in human breast milk in 1962, discovered it more and more tough to isolate this species from people over his subsequent 40-year profession. That is probably due to the microbe’s susceptibility to widespread antibiotics akin to penicillin, amoxicillin, and others.

A wealth of experimental proof, in addition to a rising variety of human scientific trials, recommend that almost all results of L. reuteri are as a result of elevated launch of oxytocin from the hypothalamus and pituitary glands within the mind, thereby making it a prototypical “psychobiotic.” Restoration of this misplaced microbe, L. reuteri, has been related to:

  • Restoration or preservation of youthful muscle and energy—Recall that we usually lose about 35% of muscle mass as we age. Whereas it might enhance energy in youthful folks, this commentary suggests L. reuteri yields a youth-preserving impact in opposition to age-related muscle loss, together with sarcopenia within the aged frail.
  • Preservation of bone densityCurrent proof suggests that there’s half as a lot bone loss with restoration of L. reuteri in comparison with placebo. That is additionally in line with observations made in experimental research (e.g., elevated osteoblast exercise in constructing the weather of bone).
  • Upkeep of sexual conduct—Animals expertise this as mating and grooming at the same time as outdated mice. People expertise this as upkeep of sexual curiosity and libido as we age.
  • Restoration of youthful immunity—Two research now doc that age-related lack of T-cell immunity as a result of atrophy of the thymus gland reverses with L. reuteri. This might probably imply that age-related lack of immunity and immunosurveillance (in opposition to look of most cancers cells) could also be addressed or reversed with restoration of this microbe.
  • Deeper, extra sustained sleep—With (actigraphically-measured) extension of REM (speedy eye-movement) intervals. This commentary is anecdotal, not but formally studied. I personally expertise it to an extravagant diploma, changing me from a persistent insomniac to somebody who enjoys deep, uninterrupted sleep each evening.
  • Acceleration of therapeutic—Pores and skin wounds inflicted on animals and people heal extra quickly, interpreted to be a gauge of youthful therapeutic responses that reach past pores and skin.
  • Discount in endotoxemia—This impact has far-reaching potential implications together with reductions in insulin resistance, blood sugar, blood strain, and different measures. That is probably a consequence of L. reuteri’s upper-GI colonizing skill and its capability to provide bacteriocins, pure antibiotics efficient in opposition to most of the species of small intestinal bacterial overgrowth, SIBO, that I imagine is epidemic within the U.S.
  • Enhance in empathy, social connection, and accepting the opinions of others—These are the results that I discover probably the most attention-grabbing. It makes you a greater member of a group, higher capable of perceive and join with different folks.

Stronger muscular tissues and bones, heightened immunity, deeper sleep, accelerated therapeutic, lowered irritation. I hope that you’re starting to understand the big implications for human well being—emotional, bodily, and social–of restoring this misplaced microbe. I don’t suppose it’s a stretch to say that L. reuteri and its increase in oxytocin make you a greater human being. It’s not about longevity; it’s about sustaining youthfulness and vigor for so long as doable. However it’s a microbe misplaced by the vast majority of folks. Restoring it, I imagine, is a genuinely enormous benefit for the human expertise. Restoration of L. reuteri received’t make a 70-year outdated right into a 20-year outdated, however I imagine it turns again the clock on most of the phenomena of getting older by 10-20 years. I don’t know of the rest that has this impact but is so benign, so accessible, and accompanied by so many different useful results.

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